Indus Scrolls English
  • Home
  • News
    • National
    • International
    • Regional
    • Environment
    • Sports
  • Opinion
  • Culture
    • Temples
    • Ayurveda
    • Art
    • Festivals
    • Books
    • Astrology
    • Literature
    • History
  • Religion
    • Our Gurus
    • Hinduism
    • Islam
    • Christianity
  • Lifestyle
    • Health
    • Yoga
    • Fashion
    • Travel
    • Cuisine
  • Science
  • Tech
  • Entertainment
  • Economy
No Result
View All Result
  • Home
  • News
    • National
    • International
    • Regional
    • Environment
    • Sports
  • Opinion
  • Culture
    • Temples
    • Ayurveda
    • Art
    • Festivals
    • Books
    • Astrology
    • Literature
    • History
  • Religion
    • Our Gurus
    • Hinduism
    • Islam
    • Christianity
  • Lifestyle
    • Health
    • Yoga
    • Fashion
    • Travel
    • Cuisine
  • Science
  • Tech
  • Entertainment
  • Economy
No Result
View All Result
Indus Scrolls English
No Result
View All Result
Home News Science

‘Hazardous chemical reagents may profoundly affect fetal health’

India Science Wire by India Science Wire
May 11, 2023
in Science
Share on FacebookShare on TwitterWhatsAppTelegram

Tetrabutylammonium bromide (TBAB) is an industrial reagent commonly found in water bodies – rivers, ponds, and ocean as an industrial by-product. Researchers from the CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad; Department of Biochemistry, Panjab University, Chandigarh; and Global Product Compliance─India, Nagpur, have studied the effect of chemical TBAB on embryonic development.

If humans consume TBAB, it causes severe brain diseases and disorders like vertigo, hallucinations, and delirium. However, the extent of environmental risk and TBAB toxicity to human health, particularly embryonic and fetal health, is still not known. This study attempts to understand one aspect of its toxicity using zebrafish as a model.

“Our results show that TBAB exposure to zebrafish embryos results in abnormalities and defects in the brain, inner ear, cartilage and bone of the head. We showed that TBAB exposure alters the embryo’s early brain and ear formation. The long-term exposure of TBAB resulted in bone and cartilage defects in the zebrafish,” says Dr Megha Kumar, the lead researcher.

TBAB is used in many products like fabric softeners, disinfectants, and sanitizers. As a result, it is widely found in water bodies.

“TBAB severely effects embryonic and fetal health,” cautions Dr Kumar.

The team exposed the zebrafish embryos to TBAB dissolved in water. They investigated the expression of genes associated with brain and inner ear development in TBAB-treated zebrafish embryos and compared it with water-treated embryos (control). They also used other molecular biology techniques – real time PCR, cell death assay, and in silico molecular docking to understand the effect of this chemical on different regions of the embryo.

TBAB treatment resulted in aberrations in the specification of the neural crest precursors, hindbrain segmentation, and otic neurogenesis. It also induced a surge in apoptosis in the developing embryo’s head, tail, and trunk regions. According to the researchers, the long-term TBAB exposure may result in cardiac edema and craniofacial defects.

The study highlights how the commonly used industrial reagents such as TBAB may profoundly affect embryonic health. Appropriate remediation measures are required to reduce the levels of such industrial effluents from the environment. Besides Dr Kumar, the team comprised Sharada Iyer (the first author), Neha Dhiman, Suraj P. Zade, Sulagna Mukherjee, and Neha Singla. The study has been published in ACS Chemical Neuroscience.  (India Science Wire)

Author

  • India Science Wire
    India Science Wire

    View all posts

ShareTweetSendShare

Related News

‘Hazardous chemical reagents may profoundly affect fetal health’
Science

Researchers find key elements affecting osmotic stress in plants

Two renewable energy labs inaugurated at IIT Roorkee
Science

Two renewable energy labs inaugurated at IIT Roorkee

Novel drug repurposing approach against COVID-19
Science

Novel drug repurposing approach against COVID-19

Fresh insights into spread of airborne pathogens in indoor spaces
Science

Fresh insights into spread of airborne pathogens in indoor spaces

Study demonstrates gold-catalyzed fundamental organometallic steps
Science

Study demonstrates gold-catalyzed fundamental organometallic steps

‘Countries need to share their technological strengths with the world for coexistence’
Science

‘Countries need to share their technological strengths with the world for coexistence’

Discussion about this post

At 84, He’s Still Taking Notes: Meet the Nuclear Scientist Pursuing an MBA at IIM Sambalpur

At 84, He’s Still Taking Notes: Meet the Nuclear Scientist Pursuing an MBA at IIM Sambalpur

68-Year-Old Woman Honoured at National Film Awards for Running Marathons Barefoot to Save Her Husband

68-Year-Old Woman Honoured at National Film Awards for Running Marathons Barefoot to Save Her Husband

Indian Seniors Redefine Love and Companionship in Their Twilight Years

Indian Seniors Redefine Love and Companionship in Their Twilight Years

Meet the 69-Year-Old ‘Weight Lifter Mummy’ Who Can Deadlift 60 Kg – And Why It’s Never Too Late to Start

Meet the 69-Year-Old ‘Weight Lifter Mummy’ Who Can Deadlift 60 Kg – And Why It’s Never Too Late to Start

From Retirement to Rooftop Renaissance: Ashok’s Green Revolution

70-Year-Old Preserves Childhood Memories in Jars, Earns ₹1.5 Lakh/Month

70-Year-Old Preserves Childhood Memories in Jars, Earns ₹1.5 Lakh/Month

Vyjayanthimala Dancing at 90: A Legacy That Endures

Vyjayanthimala Dancing at 90: A Legacy That Endures

Muktaben Dagli: A Beacon of Hope for Blind Girls

Muktaben Dagli: A Beacon of Hope for Blind Girls

India’s Surging Screen Time Raises Health and Social Concerns

India’s Surging Screen Time Raises Health and Social Concerns

Here Is The Grandeur Of Mahakumbha-2025 Never To Be Over

Here Is The Grandeur Of Mahakumbha-2025 Never To Be Over

  • Support Us
  • Our Projects
  • Our Mission
  • Contact Us

©Copyright Indus Scrolls. Tech-enabled by Ananthapuri Technologies

No Result
View All Result
  • Home
  • News
    • National
    • International
    • Regional
    • Environment
    • Sports
  • Opinion
  • Culture
    • Temples
    • Ayurveda
    • Art
    • Festivals
    • Books
    • Astrology
    • Literature
    • History
  • Religion
    • Our Gurus
    • Hinduism
    • Islam
    • Christianity
  • Lifestyle
    • Health
    • Yoga
    • Fashion
    • Travel
    • Cuisine
  • Science
  • Tech
  • Entertainment
  • Economy

©Copyright Indus Scrolls. Tech-enabled by Ananthapuri Technologies